Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage. Existing computational methods on MLS quantification not only require intensive labeling in millimeter-level measurement but also suffer from poor performance due to their dependence on specific landmarks or simplified anatomical assumptions. In this paper, we propose a novel semi-supervised framework to accurately measure the scale of MLS from head CT scans. We formulate the MLS measurement task as a deformation estimation problem and solve it using a few MLS slices with sparse labels. Meanwhile, with the help of diffusion models, we are able to use a great number of unlabeled MLS data and 2793 non-MLS cases for representation learning and regularization. The extracted representation reflects how the image is different from a non-MLS image and regularization serves an important role in the sparse-to-dense refinement of the deformation field. Our experiment on a real clinical brain hemorrhage dataset has achieved state-of-the-art performance and can generate interpretable deformation fields.

In this paper, we propose a large-scale language pre-training for text GENeration using dIffusion modEl, which is named GENIE. GENIE is a pre-training sequence-to-sequence text generation model which combines Transformer and diffusion. The diffusion model accepts the latent information from the encoder, which is used to guide the denoising of the current time step. After multiple such denoise iterations, the diffusion model can restore the Gaussian noise to the diverse output text which is controlled by the input text. Moreover, such architecture design also allows us to adopt large scale pre-training on the GENIE. We propose a novel pre-training method named continuous paragraph denoise based on the characteristics of the diffusion model. Extensive experiments on the XSum, CNN/DailyMail, and Gigaword benchmarks shows that GENIE can achieves comparable performance with various strong baselines, especially after pre-training, the generation quality of GENIE is greatly improved. We have also conduct a lot of experiments on the generation diversity and parameter impact of GENIE. The code for GENIE will be made publicly available.

Data compression is becoming critical for storing scientific data because many scientific applications need to store large amounts of data and post process this data for scientific discovery. Unlike image and video compression algorithms that limit errors to primary data, scientists require compression techniques that accurately preserve derived quantities of interest (QoIs). This paper presents a physics-informed compression technique implemented as an end-to-end, scalable, GPU-based pipeline for data compression that addresses this requirement. Our hybrid compression technique combines machine learning techniques and standard compression methods. Specifically, we combine an autoencoder, an error-bounded lossy compressor to provide guarantees on raw data error, and a constraint satisfaction post-processing step to preserve the QoIs within a minimal error (generally less than floating point error). The effectiveness of the data compression pipeline is demonstrated by compressing nuclear fusion simulation data generated by a large-scale fusion code, XGC, which produces hundreds of terabytes of data in a single day. Our approach works within the ADIOS framework and results in compression by a factor of more than 150 while requiring only a few percent of the computational resources necessary for generating the data, making the overall approach highly effective for practical scenarios.

Inspired by the recent success of Transformers for Natural Language Processing and vision Transformer for Computer Vision, many researchers in the medical imaging community have flocked to Transformer-based networks for various main stream medical tasks such as classification, segmentation, and estimation. In this study, we analyze, two recently published Transformer-based network architectures for the task of multimodal head-and-tumor segmentation and compare their performance to the de facto standard 3D segmentation network - the nnU-Net. Our results showed that modeling long-range dependencies may be helpful in cases where large structures are present and/or large field of view is needed. However, for small structures such as head-and-neck tumor, the convolution-based U-Net architecture seemed to perform well, especially when training dataset is small and computational resource is limited.

Graph-based change point detection (CPD) play an irreplaceable role in discovering anomalous graphs in the time-varying network. While several techniques have been proposed to detect change points by identifying whether there is a significant difference between the target network and successive previous ones, they neglect the natural evolution of the network. In practice, real-world graphs such as social networks, traffic networks, and rating networks are constantly evolving over time. Considering this problem, we treat the problem as a prediction task and propose a novel CPD method for dynamic graphs via a latent evolution model. Our method focuses on learning the low-dimensional representations of networks and capturing the evolving patterns of these learned latent representations simultaneously. After having the evolving patterns, a prediction of the target network can be achieved. Then, we can detect the change points by comparing the prediction and the actual network by leveraging a trade-off strategy, which balances the importance between the prediction network and the normal graph pattern extracted from previous networks. Intensive experiments conducted on both synthetic and real-world datasets show the effectiveness and superiority of our model.

Long-form numerical reasoning in financial analysis aims to generate a reasoning program to calculate the correct answer for a given question. Previous work followed a retriever-generator framework, where the retriever selects key facts from a long-form document, and the generator generates a reasoning program based on retrieved facts. However, they treated all facts equally without considering the different contributions of facts with and without numbers. Meanwhile, the program consistency were ignored under supervised training, resulting in lower training accuracy and diversity. To solve these problems, we proposed APOLLO to improve the long-form numerical reasoning framework. For the retriever, we adopt a number-aware negative sampling strategy to enable the retriever to be more discriminative on key numerical facts. For the generator, we design consistency-based reinforcement learning and target program augmentation strategy based on the consistency of program execution results. Experimental results on the FinQA and ConvFinQA leaderboard verify the effectiveness of our proposed method, achieving the new state-of-the-art.

The identification of addiction-related circuits is critical for explaining addiction processes and developing addiction treatments. And models of functional addiction circuits developed from functional imaging are an effective tool for discovering and verifying addiction circuits. However, analyzing functional imaging data of addiction and detecting functional addiction circuits still have challenges. We have developed a data-driven and end-to-end generative artificial intelligence(AI) framework to address these difficulties. The framework integrates dynamic brain network modeling and novel network architecture networks architecture, including temporal graph Transformer and contrastive learning modules. A complete workflow is formed by our generative AI framework: the functional imaging data, from neurobiological experiments, and computational modeling, to end-to-end neural networks, is transformed into dynamic nicotine addiction-related circuits. It enables the detection of addiction-related brain circuits with dynamic properties and reveals the underlying mechanisms of addiction.

In real teaching scenarios, an excellent teacher always teaches what he (or she) is good at but the student is not. This method gives the student the best assistance in making up for his (or her) weaknesses and becoming a good one overall. Enlightened by this, we introduce the approach to the knowledge distillation framework and propose a data-based distillation method named ``Teaching what you Should Teach (TST)''. To be specific, TST contains a neural network-based data augmentation module with the priori bias, which can assist in finding what the teacher is good at while the student are not by learning magnitudes and probabilities to generate suitable samples. By training the data augmentation module and the generalized distillation paradigm in turn, a student model that has excellent generalization ability can be created. To verify the effectiveness of TST, we conducted extensive comparative experiments on object recognition (CIFAR-100 and ImageNet-1k), detection (MS-COCO), and segmentation (Cityscapes) tasks. As experimentally demonstrated, TST achieves state-of-the-art performance on almost all teacher-student pairs. Furthermore, we conduct intriguing studies of TST, including how to solve the performance degradation caused by the stronger teacher and what magnitudes and probabilities are needed for the distillation framework.

To date, little attention has been given to multi-view 3D human mesh estimation, despite real-life applicability (e.g., motion capture, sport analysis) and robustness to single-view ambiguities. Existing solutions typically suffer from poor generalization performance to new settings, largely due to the limited diversity of image-mesh pairs in multi-view training data. To address this shortcoming, people have explored the use of synthetic images. But besides the usual impact of visual gap between rendered and target data, synthetic-data-driven multi-view estimators also suffer from overfitting to the camera viewpoint distribution sampled during training which usually differs from real-world distributions. Tackling both challenges, we propose a novel simulation-based training pipeline for multi-view human mesh recovery, which (a) relies on intermediate 2D representations which are more robust to synthetic-to-real domain gap; (b) leverages learnable calibration and triangulation to adapt to more diversified camera setups; and (c) progressively aggregates multi-view information in a canonical 3D space to remove ambiguities in 2D representations. Through extensive benchmarking, we demonstrate the superiority of the proposed solution especially for unseen in-the-wild scenarios.

The space-air-ground integrated network (SAGIN), one of the key technologies for next-generation mobile communication systems, can facilitate data transmission for users all over the world, especially in some remote areas where vast amounts of informative data are collected by Internet of remote things (IoRT) devices to support various data-driven artificial intelligence (AI) services. However, training AI models centrally with the assistance of SAGIN faces the challenges of highly constrained network topology, inefficient data transmission, and privacy issues. To tackle these challenges, we first propose a novel topology-aware federated learning framework for the SAGIN, namely Olive Branch Learning (OBL). Specifically, the IoRT devices in the ground layer leverage their private data to perform model training locally, while the air nodes in the air layer and the ring-structured low earth orbit (LEO) satellite constellation in the space layer are in charge of model aggregation (synchronization) at different scales.To further enhance communication efficiency and inference performance of OBL, an efficient Communication and Non-IID-aware Air node-Satellite Assignment (CNASA) algorithm is designed by taking the data class distribution of the air nodes as well as their geographic locations into account. Furthermore, we extend our OBL framework and CNASA algorithm to adapt to more complex multi-orbit satellite networks. We analyze the convergence of our OBL framework and conclude that the CNASA algorithm contributes to the fast convergence of the global model. Extensive experiments based on realistic datasets corroborate the superior performance of our algorithm over the benchmark policies.