最近的研究验证了心血管疾病（CVD）风险与视网膜眼底图像之间的关联。结合深度学习（DL）和便携式底面摄像机将在各种情况下实现CVD风险估计并改善医疗保健民主化。但是，仍然有重大问题要解决。首要问题最重要的是研究材料数据库与生产环境中样本之间的不同摄像头差异。大多数准备进行研究的高质量视网膜图数据库都是从高端底面摄像机中收集的，并且不同摄像机之间存在显着的域差异。为了充分探索域差异问题，我们首先收集了一个配对（FCP）的数据集，该数据集包含由高端TopCon视网膜摄像头捕获的配对底面图像和同一患者的低端Mediwork Portable fellus摄像头。然后，我们提出了一个跨外观特征对齐预训练方案和一个自发注意的摄像头适配器模块，以提高模型的鲁棒性。交叉效力特征对齐训练鼓励模型从同一患者的左右眼底图像中学习常识，并改善模型的概括。同时，设备适应模块学习了从目标域到源域的特征转换。我们对英国生物银行数据库和我们的FCP数据进行了全面的实验。实验结果表明，通过我们提出的方法，提高了CVD风险回归准确性和两个摄像头的结果一致性。该代码可在此处找到：\ url {https://github.com/linzhlalala/cvd-risk-lasike-base--on-retinal-fundus-images-images}

医学视觉问题应答（VQA）是医疗人工智能和流行的VQA挑战的组合。鉴于医学形象和在自然语言中的临床相关问题，预计医疗VQA系统将预测符号和令人信服的答案。虽然一般域VQA已被广泛研究，但医疗VQA仍然需要特定的调查和探索，因为它的任务特征是。在本调查的第一部分，我们涵盖并讨论了关于数据源，数据数量和任务功能的公开可用的医疗VQA数据集。在第二部分中，我们审查了医疗VQA任务中使用的方法。在最后，我们分析了该领域的一些有效的挑战，并讨论了未来的研究方向。

Designing experiments often requires balancing between learning about the true treatment effects and earning from allocating more samples to the superior treatment. While optimal algorithms for the Multi-Armed Bandit Problem (MABP) provide allocation policies that optimally balance learning and earning, they tend to be computationally expensive. The Gittins Index (GI) is a solution to the MABP that can simultaneously attain optimality and computationally efficiency goals, and it has been recently used in experiments with Bernoulli and Gaussian rewards. For the first time, we present a modification of the GI rule that can be used in experiments with exponentially-distributed rewards. We report its performance in simulated 2- armed and 3-armed experiments. Compared to traditional non-adaptive designs, our novel GI modified design shows operating characteristics comparable in learning (e.g. statistical power) but substantially better in earning (e.g. direct benefits). This illustrates the potential that designs using a GI approach to allocate participants have to improve participant benefits, increase efficiencies, and reduce experimental costs in adaptive multi-armed experiments with exponential rewards.

Transformer has achieved impressive successes for various computer vision tasks. However, most of existing studies require to pretrain the Transformer backbone on a large-scale labeled dataset (e.g., ImageNet) for achieving satisfactory performance, which is usually unavailable for medical images. Additionally, due to the gap between medical and natural images, the improvement generated by the ImageNet pretrained weights significantly degrades while transferring the weights to medical image processing tasks. In this paper, we propose Bootstrap Own Latent of Transformer (BOLT), a self-supervised learning approach specifically for medical image classification with the Transformer backbone. Our BOLT consists of two networks, namely online and target branches, for self-supervised representation learning. Concretely, the online network is trained to predict the target network representation of the same patch embedding tokens with a different perturbation. To maximally excavate the impact of Transformer from limited medical data, we propose an auxiliary difficulty ranking task. The Transformer is enforced to identify which branch (i.e., online/target) is processing the more difficult perturbed tokens. Overall, the Transformer endeavours itself to distill the transformation-invariant features from the perturbed tokens to simultaneously achieve difficulty measurement and maintain the consistency of self-supervised representations. The proposed BOLT is evaluated on three medical image processing tasks, i.e., skin lesion classification, knee fatigue fracture grading and diabetic retinopathy grading. The experimental results validate the superiority of our BOLT for medical image classification, compared to ImageNet pretrained weights and state-of-the-art self-supervised learning approaches.

Text clustering and topic extraction are two important tasks in text mining. Usually, these two tasks are performed separately. For topic extraction to facilitate clustering, we can first project texts into a topic space and then perform a clustering algorithm to obtain clusters. To promote topic extraction by clustering, we can first obtain clusters with a clustering algorithm and then extract cluster-specific topics. However, this naive strategy ignores the fact that text clustering and topic extraction are strongly correlated and follow a chicken-and-egg relationship. Performing them separately fails to make them mutually benefit each other to achieve the best overall performance. In this paper, we propose an unsupervised text clustering and topic extraction framework (ClusTop) which integrates text clustering and topic extraction into a unified framework and can achieve high-quality clustering result and extract topics from each cluster simultaneously. Our framework includes four components: enhanced language model training, dimensionality reduction, clustering and topic extraction, where the enhanced language model can be viewed as a bridge between clustering and topic extraction. On one hand, it provides text embeddings with a strong cluster structure which facilitates effective text clustering; on the other hand, it pays high attention on the topic related words for topic extraction because of its self-attention architecture. Moreover, the training of enhanced language model is unsupervised. Experiments on two datasets demonstrate the effectiveness of our framework and provide benchmarks for different model combinations in this framework.

This paper illustrates the technologies of user next intent prediction with a concept knowledge graph. The system has been deployed on the Web at Alipay, serving more than 100 million daily active users. Specifically, we propose AlipayKG to explicitly characterize user intent, which is an offline concept knowledge graph in the Life-Service domain modeling the historical behaviors of users, the rich content interacted by users and the relations between them. We further introduce a Transformer-based model which integrates expert rules from the knowledge graph to infer the online user's next intent. Experimental results demonstrate that the proposed system can effectively enhance the performance of the downstream tasks while retaining explainability.

Capturing feature information effectively is of great importance in vision tasks. With the development of convolutional neural networks (CNNs), concepts like residual connection and multiple scales promote continual performance gains on diverse deep learning vision tasks. However, the existing methods do not organically combined advantages of these valid ideas. In this paper, we propose a novel CNN architecture called GoogLe2Net, it consists of residual feature-reutilization inceptions (ResFRI) or split residual feature-reutilization inceptions (Split-ResFRI) which create transverse passages between adjacent groups of convolutional layers to enable features flow to latter processing branches and possess residual connections to better process information. Our GoogLe2Net is able to reutilize information captured by foregoing groups of convolutional layers and express multi-scale features at a fine-grained level, which improves performances in image classification. And the inception we proposed could be embedded into inception-like networks directly without any migration costs. Moreover, in experiments based on popular vision datasets, such as CIFAR10 (97.94%), CIFAR100 (85.91%) and Tiny Imagenet (70.54%), we obtain better results on image classification task compared with other modern models.

Despite some successful applications of goal-driven navigation, existing deep reinforcement learning-based approaches notoriously suffers from poor data efficiency issue. One of the reasons is that the goal information is decoupled from the perception module and directly introduced as a condition of decision-making, resulting in the goal-irrelevant features of the scene representation playing an adversary role during the learning process. In light of this, we present a novel Goal-guided Transformer-enabled reinforcement learning (GTRL) approach by considering the physical goal states as an input of the scene encoder for guiding the scene representation to couple with the goal information and realizing efficient autonomous navigation. More specifically, we propose a novel variant of the Vision Transformer as the backbone of the perception system, namely Goal-guided Transformer (GoT), and pre-train it with expert priors to boost the data efficiency. Subsequently, a reinforcement learning algorithm is instantiated for the decision-making system, taking the goal-oriented scene representation from the GoT as the input and generating decision commands. As a result, our approach motivates the scene representation to concentrate mainly on goal-relevant features, which substantially enhances the data efficiency of the DRL learning process, leading to superior navigation performance. Both simulation and real-world experimental results manifest the superiority of our approach in terms of data efficiency, performance, robustness, and sim-to-real generalization, compared with other state-of-art baselines. Demonstration videos are available at \colorb{https://youtu.be/93LGlGvaN0c.

Despite the success of large language models (LLMs) in various natural language processing (NLP) tasks, the stored knowledge in these models may inevitably be incomplete, out-of-date, or incorrect. This motivates the need to utilize external knowledge to assist LLMs. Unfortunately, current methods for incorporating external knowledge often require additional training or fine-tuning, which can be costly and may not be feasible for LLMs. To address this issue, we propose a novel post-processing approach, rethinking with retrieval (RR), which retrieves relevant external knowledge based on the decomposed reasoning steps obtained from the chain-of-thought (CoT) prompting. This lightweight approach does not require additional training or fine-tuning and is not limited by the input length of LLMs. We evaluate the effectiveness of RR through extensive experiments with GPT-3 on three complex reasoning tasks: commonsense reasoning, temporal reasoning, and tabular reasoning. Our results show that RR can produce more faithful explanations and improve the performance of LLMs.

Multi-fidelity Kriging model is a promising technique in surrogate-based design as it can balance the model accuracy and cost of sample preparation by fusing low- and high-fidelity data. However, the cost for building a multi-fidelity Kriging model increases significantly with the increase of the problem dimension. To attack this issue, an efficient Hierarchical Kriging modeling method is proposed. In building the low-fidelity model, the maximal information coefficient is utilized to calculate the relative value of the hyperparameter. With this, the maximum likelihood estimation problem for determining the hyperparameters is transformed as a one-dimension optimization problem, which can be solved in an efficient manner and thus improve the modeling efficiency significantly. A local search is involved further to exploit the search space of hyperparameters to improve the model accuracy. The high-fidelity model is built in a similar manner with the hyperparameter of the low-fidelity model served as the relative value of the hyperparameter for high-fidelity model. The performance of the proposed method is compared with the conventional tuning strategy, by testing them over ten analytic problems and an engineering problem of modeling the isentropic efficiency of a compressor rotor. The empirical results demonstrate that the modeling time of the proposed method is reduced significantly without sacrificing the model accuracy. For the modeling of the isentropic efficiency of the compressor rotor, the cost saving associated with the proposed method is about 90% compared with the conventional strategy. Meanwhile, the proposed method achieves higher accuracy.