基于机器学习的分子片段连接的最新发展已经证明了通知生成过程与指定碎片的相对取向的结构信息的重要性。然而，这种结构信息尚未以完整的相对坐标系的形式提供。用于分离的键合长度，键合角和扭转角的数学细节被阐述，并且对坐标系进行了完成。在数值上对产生的接头质量产生重大影响。研究了不同类型自由度内的可靠信息的数量。进行消融研究和信息理论分析。呈现的好处建议将完整和解耦的相对坐标系应用于接头设计中的标准良好做法。

事件模式是结构化知识来源，定义了典型的真实情景（例如，去机场）。我们基于新颖的脚本感应系统和允许非专家“程序”复杂事件结构的精心设计的界面，提出了一个框架的架构库的高效循环构造框架。与此工作相关联我们释放了一个模式库：232的机器可读资源，详细的事件模式，其中每个项目都描述了其相关子事件结构（方案中发生的事情）的不同典型方案，参与者（谁扮演在场景中的角色），每个参与者的细粒度打字，以及它们之间的隐含关系约束。我们制作我们的模式库和在线提供的架构界面。

The release of ChatGPT, a language model capable of generating text that appears human-like and authentic, has gained significant attention beyond the research community. We expect that the convincing performance of ChatGPT incentivizes users to apply it to a variety of downstream tasks, including prompting the model to simplify their own medical reports. To investigate this phenomenon, we conducted an exploratory case study. In a questionnaire, we asked 15 radiologists to assess the quality of radiology reports simplified by ChatGPT. Most radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient. Nevertheless, instances of incorrect statements, missed key medical findings, and potentially harmful passages were reported. While further studies are needed, the initial insights of this study indicate a great potential in using large language models like ChatGPT to improve patient-centered care in radiology and other medical domains.

The SINDy algorithm has been successfully used to identify the governing equations of dynamical systems from time series data. In this paper, we argue that this makes SINDy a potentially useful tool for causal discovery and that existing tools for causal discovery can be used to dramatically improve the performance of SINDy as tool for robust sparse modeling and system identification. We then demonstrate empirically that augmenting the SINDy algorithm with tools from causal discovery can provides engineers with a tool for learning causally robust governing equations.

Effective management of public shared spaces such as car parking space, is one challenging transformational aspect for many cities, especially in the developing World. By leveraging sensing technologies, cloud computing, and Artificial Intelligence, Cities are increasingly being managed smartly. Smart Cities not only bring convenience to City dwellers, but also improve their quality of life as advocated for by United Nations in the 2030 Sustainable Development Goal on Sustainable Cities and Communities. Through integration of Internet of Things and Cloud Computing, this paper presents a successful proof-of-concept implementation of a framework for managing public car parking spaces. Reservation of parking slots is done through a cloud-hosted application, while access to and out of the parking slot is enabled through Radio Frequency Identification (RFID) technology which in real-time, accordingly triggers update of the parking slot availability in the cloud-hosted database. This framework could bring considerable convenience to City dwellers since motorists only have to drive to a parking space when sure of a vacant parking slot, an important stride towards realization of sustainable smart cities and communities.

Despite recent success in large language model (LLM) reasoning, LLMs still struggle with hierarchical multi-step reasoning like generating complex programs. In these cases, humans often start with a high-level algorithmic design and implement each part gradually. We introduce Parsel, a framework enabling automatic implementation and validation of complex algorithms with code LLMs, based on hierarchical function descriptions in natural language. Parsel can be used across domains requiring hierarchical reasoning, e.g. code synthesis, theorem proving, and robotic planning. We demonstrate Parsel's capabilities by using it to generate complex programs that cannot currently be automatically implemented from one description and backtranslating Python programs in the APPS dataset. Beyond modeling capabilities, Parsel allows problem-solving with high-level algorithmic designs, benefiting both students and professional programmers.

Current image generation models struggle to reliably produce well-formed visual text. In this paper, we investigate a key contributing factor: popular text-to-image models lack character-level input features, making it much harder to predict a word's visual makeup as a series of glyphs. To quantify the extent of this effect, we conduct a series of controlled experiments comparing character-aware vs. character-blind text encoders. In the text-only domain, we find that character-aware models provide large gains on a novel spelling task (WikiSpell). Transferring these learnings onto the visual domain, we train a suite of image generation models, and show that character-aware variants outperform their character-blind counterparts across a range of novel text rendering tasks (our DrawText benchmark). Our models set a much higher state-of-the-art on visual spelling, with 30+ point accuracy gains over competitors on rare words, despite training on far fewer examples.

Large "instruction-tuned" language models (finetuned to respond to instructions) have demonstrated a remarkable ability to generalize zero-shot to new tasks. Nevertheless, they depend heavily on human-written instruction data that is limited in quantity, diversity, and creativity, therefore hindering the generality of the tuned model. We introduce Self-Instruct, a framework for improving the instruction-following capabilities of pretrained language models by bootstrapping off its own generations. Our pipeline generates instruction, input, and output samples from a language model, then prunes them before using them to finetune the original model. Applying our method to vanilla GPT3, we demonstrate a 33% absolute improvement over the original model on Super-NaturalInstructions, on par with the performance of InstructGPT_001, which is trained with private user data and human annotations. For further evaluation, we curate a set of expert-written instructions for novel tasks, and show through human evaluation that tuning GPT3 with Self-Instruct outperforms using existing public instruction datasets by a large margin, leaving only a 5% absolute gap behind InstructGPT_001. Self-Instruct provides an almost annotation-free method for aligning pre-trained language models with instructions, and we release our large synthetic dataset to facilitate future studies on instruction tuning.

Language models have recently achieved strong performance across a wide range of NLP benchmarks. However, unlike benchmarks, real world tasks are often poorly specified, and agents must deduce the user's intended behavior from a combination of context, instructions, and examples. We investigate how both humans and models behave in the face of such task ambiguity by proposing AmbiBench, a new benchmark of six ambiguously-specified classification tasks. We evaluate humans and models on AmbiBench by seeing how well they identify the intended task using 1) instructions with varying degrees of ambiguity, and 2) different numbers of labeled examples. We find that the combination of model scaling (to 175B parameters) and training with human feedback data enables models to approach or exceed the accuracy of human participants across tasks, but that either one alone is not sufficient. In addition, we show how to dramatically improve the accuracy of language models trained without large-scale human feedback training by finetuning on a small number of ambiguous in-context examples, providing a promising direction for teaching models to generalize well in the face of ambiguity.

We introduce INSTRUCTOR, a new method for computing text embeddings given task instructions: every text input is embedded together with instructions explaining the use case (e.g., task and domain descriptions). Unlike encoders from prior work that are more specialized, INSTRUCTOR is a single embedder that can generate text embeddings tailored to different downstream tasks and domains, without any further training. We first annotate instructions for 330 diverse tasks and train INSTRUCTOR on this multitask mixture with a contrastive loss. We evaluate INSTRUCTOR on 70 embedding evaluation tasks (66 of which are unseen during training), ranging from classification and information retrieval to semantic textual similarity and text generation evaluation. INSTRUCTOR, while having an order of magnitude fewer parameters than the previous best model, achieves state-of-the-art performance, with an average improvement of 3.4% compared to the previous best results on the 70 diverse datasets. Our analysis suggests that INSTRUCTOR is robust to changes in instructions, and that instruction finetuning mitigates the challenge of training a single model on diverse datasets.