在许多图像引导的临床方法中，医学图像分割是一个基本和关键的步骤。基于深度学习的细分方法的最新成功通常取决于大量标记的数据，这特别困难且昂贵，尤其是在医学成像领域中，只有专家才能提供可靠和准确的注释。半监督学习已成为一种吸引人的策略，并广泛应用于医学图像分割任务，以训练注释有限的深层模型。在本文中，我们对最近提议的半监督学习方法进行了全面综述，并总结了技术新颖性和经验结果。此外，我们分析和讨论现有方法的局限性和几个未解决的问题。我们希望这篇评论可以激发研究界探索解决这一挑战的解决方案，并进一步促进医学图像细分领域的发展。

医学图像分割是许多临床方法的基本和关键步骤。半监督学习已被广​​泛应用于医学图像分割任务，因为它减轻了收购专家审查的注释的沉重负担，并利用了更容易获得的未标记数据的优势。虽然已被证明是通过实施不同分布下的预测的不变性的一致性学习，但现有方法无法充分利用来自未标记数据的区域级形状约束和边界级距离信息。在本文中，我们提出了一种新颖的不确定性引导的相互一致学习框架，通过将任务中的一致性学习与自组合和交叉任务一致性学习从任务级正则化的最新预测集成了任务内的一致性学习，从而有效地利用了未标记的数据利用几何形状信息。该框架是由模型的估计分割不确定性指导，以便为一致性学习选择相对某些预测，以便有效地利用来自未标记数据的更可靠的信息。我们在两个公开的基准数据集中广泛地验证了我们提出的方法：左心房分割（LA）数据集和大脑肿瘤分割（BRATS）数据集。实验结果表明，我们的方法通过利用未标记的数据和优于现有的半监督分段方法来实现性能增益。

Embedding words in vector space is a fundamental first step in state-of-the-art natural language processing (NLP). Typical NLP solutions employ pre-defined vector representations to improve generalization by co-locating similar words in vector space. For instance, Word2Vec is a self-supervised predictive model that captures the context of words using a neural network. Similarly, GLoVe is a popular unsupervised model incorporating corpus-wide word co-occurrence statistics. Such word embedding has significantly boosted important NLP tasks, including sentiment analysis, document classification, and machine translation. However, the embeddings are dense floating-point vectors, making them expensive to compute and difficult to interpret. In this paper, we instead propose to represent the semantics of words with a few defining words that are related using propositional logic. To produce such logical embeddings, we introduce a Tsetlin Machine-based autoencoder that learns logical clauses self-supervised. The clauses consist of contextual words like "black," "cup," and "hot" to define other words like "coffee," thus being human-understandable. We evaluate our embedding approach on several intrinsic and extrinsic benchmarks, outperforming GLoVe on six classification tasks. Furthermore, we investigate the interpretability of our embedding using the logical representations acquired during training. We also visualize word clusters in vector space, demonstrating how our logical embedding co-locate similar words.

Model bias triggered by long-tailed data has been widely studied. However, measure based on the number of samples cannot explicate three phenomena simultaneously: (1) Given enough data, the classification performance gain is marginal with additional samples. (2) Classification performance decays precipitously as the number of training samples decreases when there is insufficient data. (3) Model trained on sample-balanced datasets still has different biases for different classes. In this work, we define and quantify the semantic scale of classes, which is used to measure the feature diversity of classes. It is exciting to find experimentally that there is a marginal effect of semantic scale, which perfectly describes the first two phenomena. Further, the quantitative measurement of semantic scale imbalance is proposed, which can accurately reflect model bias on multiple datasets, even on sample-balanced data, revealing a novel perspective for the study of class imbalance. Due to the prevalence of semantic scale imbalance, we propose semantic-scale-balanced learning, including a general loss improvement scheme and a dynamic re-weighting training framework that overcomes the challenge of calculating semantic scales in real-time during iterations. Comprehensive experiments show that dynamic semantic-scale-balanced learning consistently enables the model to perform superiorly on large-scale long-tailed and non-long-tailed natural and medical datasets, which is a good starting point for mitigating the prevalent but unnoticed model bias.

Tsetlin Machine (TM) has been gaining popularity as an inherently interpretable machine leaning method that is able to achieve promising performance with low computational complexity on a variety of applications. The interpretability and the low computational complexity of the TM are inherited from the Boolean expressions for representing various sub-patterns. Although possessing favorable properties, TM has not been the go-to method for AI applications, mainly due to its conceptual and theoretical differences compared with perceptrons and neural networks, which are more widely known and well understood. In this paper, we provide detailed insights for the operational concept of the TM, and try to bridge the gap in the theoretical understanding between the perceptron and the TM. More specifically, we study the operational concept of the TM following the analytical structure of perceptrons, showing the resemblance between the perceptrons and the TM. Through the analysis, we indicated that the TM's weight update can be considered as a special case of the gradient weight update. We also perform an empirical analysis of TM by showing the flexibility in determining the clause length, visualization of decision boundaries and obtaining interpretable boolean expressions from TM. In addition, we also discuss the advantages of TM in terms of its structure and its ability to solve more complex problems.

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep learning methods, some models with good performance have emerged, but the generalization ability should be further strengthened. In this paper, we propose a two-stage mitosis segmentation and classification method, named SCMitosis. Firstly, the segmentation performance with a high recall rate is achieved by the proposed depthwise separable convolution residual block and channel-spatial attention gate. Then, a classification network is cascaded to further improve the detection performance of mitosis nuclei. The proposed model is verified on the ICPR 2012 dataset, and the highest F-score value of 0.8687 is obtained compared with the current state-of-the-art algorithms. In addition, the model also achieves good performance on GZMH dataset, which is prepared by our group and will be firstly released with the publication of this paper. The code will be available at: https://github.com/antifen/mitosis-nuclei-segmentation.

The stock market prediction has been a traditional yet complex problem researched within diverse research areas and application domains due to its non-linear, highly volatile and complex nature. Existing surveys on stock market prediction often focus on traditional machine learning methods instead of deep learning methods. Deep learning has dominated many domains, gained much success and popularity in recent years in stock market prediction. This motivates us to provide a structured and comprehensive overview of the research on stock market prediction focusing on deep learning techniques. We present four elaborated subtasks of stock market prediction and propose a novel taxonomy to summarize the state-of-the-art models based on deep neural networks from 2011 to 2022. In addition, we also provide detailed statistics on the datasets and evaluation metrics commonly used in the stock market. Finally, we highlight some open issues and point out several future directions by sharing some new perspectives on stock market prediction.

To improve the performance of the dual-encoder retriever, one effective approach is knowledge distillation from the cross-encoder ranker. Existing works construct the candidate passages following the supervised learning setting where a query is paired with a positive passage and a batch of negatives. However, through empirical observation, we find that even the hard negatives from advanced methods are still too trivial for the teacher to distinguish, preventing the teacher from transferring abundant dark knowledge to the student through its soft label. To alleviate this issue, we propose ADAM, a knowledge distillation framework that can better transfer the dark knowledge held in the teacher with Adaptive Dark exAMples. Different from previous works that only rely on one positive and hard negatives as candidate passages, we create dark examples that all have moderate relevance to the query through mixing-up and masking in discrete space. Furthermore, as the quality of knowledge held in different training instances varies as measured by the teacher's confidence score, we propose a self-paced distillation strategy that adaptively concentrates on a subset of high-quality instances to conduct our dark-example-based knowledge distillation to help the student learn better. We conduct experiments on two widely-used benchmarks and verify the effectiveness of our method.

Bilevel optimization plays an essential role in many machine learning tasks, ranging from hyperparameter optimization to meta-learning. Existing studies on bilevel optimization, however, focus on either centralized or synchronous distributed setting. The centralized bilevel optimization approaches require collecting massive amount of data to a single server, which inevitably incur significant communication expenses and may give rise to data privacy risks. Synchronous distributed bilevel optimization algorithms, on the other hand, often face the straggler problem and will immediately stop working if a few workers fail to respond. As a remedy, we propose Asynchronous Distributed Bilevel Optimization (ADBO) algorithm. The proposed ADBO can tackle bilevel optimization problems with both nonconvex upper-level and lower-level objective functions, and its convergence is theoretically guaranteed. Furthermore, it is revealed through theoretic analysis that the iteration complexity of ADBO to obtain the $\epsilon$-stationary point is upper bounded by $\mathcal{O}(\frac{1}{{{\epsilon ^2}}})$. Thorough empirical studies on public datasets have been conducted to elucidate the effectiveness and efficiency of the proposed ADBO.

The dual-encoder has become the de facto architecture for dense retrieval. Typically, it computes the latent representations of the query and document independently, thus failing to fully capture the interactions between the query and document. To alleviate this, recent work expects to get query-informed representations of documents. During training, it expands the document with a real query, while replacing the real query with a generated pseudo query at inference. This discrepancy between training and inference makes the dense retrieval model pay more attention to the query information but ignore the document when computing the document representation. As a result, it even performs worse than the vanilla dense retrieval model, since its performance depends heavily on the relevance between the generated queries and the real query. In this paper, we propose a curriculum sampling strategy, which also resorts to the pseudo query at training and gradually increases the relevance of the generated query to the real query. In this way, the retrieval model can learn to extend its attention from the document only to both the document and query, hence getting high-quality query-informed document representations. Experimental results on several passage retrieval datasets show that our approach outperforms the previous dense retrieval methods1.