The necessity of data driven decisions in healthcare strategy formulation is rapidly increasing. A reliable framework which helps identify factors impacting a Healthcare Provider Facility or a Hospital (from here on termed as Facility) Market Share is of key importance. This pilot study aims at developing a data driven Machine Learning - Regression framework which aids strategists in formulating key decisions to improve the Facilitys Market Share which in turn impacts in improving the quality of healthcare services. The US (United States) healthcare business is chosen for the study; and the data spanning across 60 key Facilities in Washington State and about 3 years of historical data is considered. In the current analysis Market Share is termed as the ratio of facility encounters to the total encounters among the group of potential competitor facilities. The current study proposes a novel two-pronged approach of competitor identification and regression approach to evaluate and predict market share, respectively. Leveraged model agnostic technique, SHAP, to quantify the relative importance of features impacting the market share. The proposed method to identify pool of competitors in current analysis, develops Directed Acyclic Graphs (DAGs), feature level word vectors and evaluates the key connected components at facility level. This technique is robust since its data driven which minimizes the bias from empirical techniques. Post identifying the set of competitors among facilities, developed Regression model to predict the Market share. For relative quantification of features at a facility level, incorporated SHAP a model agnostic explainer. This helped to identify and rank the attributes at each facility which impacts the market share.

有监督的深度学习算法具有自动化筛查，监视和分级的医学图像的巨大潜力。但是，培训表现模型通常需要大量的标记数据，这在医疗领域几乎无法获得。自我监督的对比框架通过首先从未标记的图像中学习来放松这种依赖性。在这项工作中，我们表明使用两种对比方法进行了预处理，即SIMCLR和BYOL，就与年龄相关的黄斑变性（AMD）的临床评估有关深度学习的实用性。在实验中，使用两个大型临床数据集，其中包含7,912名患者的170,427个光学相干断层扫描（OCT）图像，我们评估了从AMD阶段和类型分类到功能性终点的七个下游任务，从七个下游任务进行预处理，从在标签较少的七个任务中，六个任务中有六个显着增加。但是，标准的对比框架具有两个已知的弱点，这些弱点不利于医疗领域的预处理。用于创建正面对比对的几种图像转换不适用于灰度医学扫描。此外，医学图像通常描绘了相同的解剖区域和疾病的严重程度，从而导致许多误导性负面对。为了解决这些问题，我们开发了一种新颖的元数据增强方法，该方法利用了丰富的固有可用患者信息集。为此，我们采用了患者身份，眼睛位置（即左或右）和时间序列数据的记录，以指示典型的不可知的对比关系。通过利用这种经常被忽视的信息，我们元数据增强的对比预处理可带来进一步的好处，并且在下游七个任务中有五个任务中的五个中的五分之一。

异常检测涉及识别不符合预期行为的数据集中的示例。虽然存在大量的异常检测算法，但是已经支付了很少的注意，以解释这些算法标志某些示例作为异常的原因。然而，这样的解释对于解释算法输出的任何人来说可能非常有用。本文开发了一种解释最先进的隔离森林异常检测算法的异常预测的方法。该方法输出解释载体，该解释矢量捕获示例的每个属性的重要性是如何将其识别为异常。合成和现实世界数据集的彻底实验评估表明，我们的方法比大多数现代最先进的解释性方法更准确，更有效。