Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

Federated learning (FL) enables the building of robust and generalizable AI models by leveraging diverse datasets from multiple collaborators without centralizing the data. We created NVIDIA FLARE as an open-source software development kit (SDK) to make it easier for data scientists to use FL in their research and real-world applications. The SDK includes solutions for state-of-the-art FL algorithms and federated machine learning approaches, which facilitate building workflows for distributed learning across enterprises and enable platform developers to create a secure, privacy-preserving offering for multiparty collaboration utilizing homomorphic encryption or differential privacy. The SDK is a lightweight, flexible, and scalable Python package, and allows researchers to bring their data science workflows implemented in any training libraries (PyTorch, TensorFlow, XGBoost, or even NumPy) and apply them in real-world FL settings. This paper introduces the key design principles of FLARE and illustrates some use cases (e.g., COVID analysis) with customizable FL workflows that implement different privacy-preserving algorithms. Code is available at https://github.com/NVIDIA/NVFlare.

常规的自我监督单眼深度预测方法基于静态环境假设，这导致由于对象运动引入的不匹配和遮挡问题而导致动态场景的准确性降解。现有的以动态对象为中心的方法仅部分解决了训练损失级别的不匹配问题。在本文中，我们因此提出了一种新型的多帧单眼预测方法，以在预测和监督损失水平上解决这些问题。我们的方法称为DynamicDepth，是一个新框架，该框架是通过自我监督周期一致的学习方案训练的。提出了动态对象运动解开（DOMD）模块以解开对象运动以解决不匹配问题。此外，新颖的闭塞成本量和重新投射损失旨在减轻对象运动的闭塞作用。对CityScapes和Kitti数据集进行的广泛分析和实验表明，我们的方法显着优于最先进的单眼深度预测方法，尤其是在动态对象的领域。代码可从https://github.com/autoailab/dynamicdepth获得

自我监督的单眼深度预测提供了一种经济有效的解决方案，以获得每个像素的3D位置。然而，现有方法通常会导致不满意的准确性，这对于自治机器人至关重要。在本文中，我们提出了一种新的两级网络，通过利用低成本稀疏（例如4梁）LIDAR来推进自我监督单眼密集深度学习。与使用稀疏激光雷达的现有方法不同，主要以耗时的迭代后处理，我们的模型保留单眼图像特征和稀疏的LIDAR功能，以预测初始深度图。然后，有效的前馈细化网络进一步设计为校正伪3D空间中这些初始深度图中的错误，其具有实时性能。广泛的实验表明，我们所提出的模型显着优于所有最先进的自我监控方法，以及基于稀疏的激光器的方法，以及对自我监督单眼深度预测和完成任务。通过精确的密集深度预测，我们的模型优于基于最先进的稀疏激光雷达的方法（伪LIDAR ++）在Kitti排行榜上下游任务单眼3D对象检测超过68％。代码可在https://github.com/autoailab/fusiondepth获得

Increasing research interests focus on sequential recommender systems, aiming to model dynamic sequence representation precisely. However, the most commonly used loss function in state-of-the-art sequential recommendation models has essential limitations. To name a few, Bayesian Personalized Ranking (BPR) loss suffers the vanishing gradient problem from numerous negative sampling and predictionbiases; Binary Cross-Entropy (BCE) loss subjects to negative sampling numbers, thereby it is likely to ignore valuable negative examples and reduce the training efficiency; Cross-Entropy (CE) loss only focuses on the last timestamp of the training sequence, which causes low utilization of sequence information and results in inferior user sequence representation. To avoid these limitations, in this paper, we propose to calculate Cumulative Cross-Entropy (CCE) loss over the sequence. CCE is simple and direct, which enjoys the virtues of painless deployment, no negative sampling, and effective and efficient training. We conduct extensive experiments on five benchmark datasets to demonstrate the effectiveness and efficiency of CCE. The results show that employing CCE loss on three state-of-the-art models GRU4Rec, SASRec, and S3-Rec can reach 125.63%, 69.90%, and 33.24% average improvement of full ranking NDCG@5, respectively. Using CCE, the performance curve of the models on the test data increases rapidly with the wall clock time, and is superior to that of other loss functions in almost the whole process of model training.

In the scenario of black-box adversarial attack, the target model's parameters are unknown, and the attacker aims to find a successful adversarial perturbation based on query feedback under a query budget. Due to the limited feedback information, existing query-based black-box attack methods often require many queries for attacking each benign example. To reduce query cost, we propose to utilize the feedback information across historical attacks, dubbed example-level adversarial transferability. Specifically, by treating the attack on each benign example as one task, we develop a meta-learning framework by training a meta-generator to produce perturbations conditioned on benign examples. When attacking a new benign example, the meta generator can be quickly fine-tuned based on the feedback information of the new task as well as a few historical attacks to produce effective perturbations. Moreover, since the meta-train procedure consumes many queries to learn a generalizable generator, we utilize model-level adversarial transferability to train the meta-generator on a white-box surrogate model, then transfer it to help the attack against the target model. The proposed framework with the two types of adversarial transferability can be naturally combined with any off-the-shelf query-based attack methods to boost their performance, which is verified by extensive experiments.

Supervised Deep-Learning (DL)-based reconstruction algorithms have shown state-of-the-art results for highly-undersampled dynamic Magnetic Resonance Imaging (MRI) reconstruction. However, the requirement of excessive high-quality ground-truth data hinders their applications due to the generalization problem. Recently, Implicit Neural Representation (INR) has appeared as a powerful DL-based tool for solving the inverse problem by characterizing the attributes of a signal as a continuous function of corresponding coordinates in an unsupervised manner. In this work, we proposed an INR-based method to improve dynamic MRI reconstruction from highly undersampled k-space data, which only takes spatiotemporal coordinates as inputs. Specifically, the proposed INR represents the dynamic MRI images as an implicit function and encodes them into neural networks. The weights of the network are learned from sparsely-acquired (k, t)-space data itself only, without external training datasets or prior images. Benefiting from the strong implicit continuity regularization of INR together with explicit regularization for low-rankness and sparsity, our proposed method outperforms the compared scan-specific methods at various acceleration factors. E.g., experiments on retrospective cardiac cine datasets show an improvement of 5.5 ~ 7.1 dB in PSNR for extremely high accelerations (up to 41.6-fold). The high-quality and inner continuity of the images provided by INR has great potential to further improve the spatiotemporal resolution of dynamic MRI, without the need of any training data.

Recent studies have shown that using an external Language Model (LM) benefits the end-to-end Automatic Speech Recognition (ASR). However, predicting tokens that appear less frequently in the training set is still quite challenging. The long-tail prediction problems have been widely studied in many applications, but only been addressed by a few studies for ASR and LMs. In this paper, we propose a new memory augmented lookup dictionary based Transformer architecture for LM. The newly introduced lookup dictionary incorporates rich contextual information in training set, which is vital to correctly predict long-tail tokens. With intensive experiments on Chinese and English data sets, our proposed method is proved to outperform the baseline Transformer LM by a great margin on both word/character error rate and tail tokens error rate. This is achieved without impact on the decoding efficiency. Overall, we demonstrate the effectiveness of our proposed method in boosting the ASR decoding performance, especially for long-tail tokens.

The objective of this paper is to learn dense 3D shape correspondence for topology-varying generic objects in an unsupervised manner. Conventional implicit functions estimate the occupancy of a 3D point given a shape latent code. Instead, our novel implicit function produces a probabilistic embedding to represent each 3D point in a part embedding space. Assuming the corresponding points are similar in the embedding space, we implement dense correspondence through an inverse function mapping from the part embedding vector to a corresponded 3D point. Both functions are jointly learned with several effective and uncertainty-aware loss functions to realize our assumption, together with the encoder generating the shape latent code. During inference, if a user selects an arbitrary point on the source shape, our algorithm can automatically generate a confidence score indicating whether there is a correspondence on the target shape, as well as the corresponding semantic point if there is one. Such a mechanism inherently benefits man-made objects with different part constitutions. The effectiveness of our approach is demonstrated through unsupervised 3D semantic correspondence and shape segmentation.

Patients take care of what their teeth will be like after the orthodontics. Orthodontists usually describe the expectation movement based on the original smile images, which is unconvincing. The growth of deep-learning generative models change this situation. It can visualize the outcome of orthodontic treatment and help patients foresee their future teeth and facial appearance. While previous studies mainly focus on 2D or 3D virtual treatment outcome (VTO) at a profile level, the problem of simulating treatment outcome at a frontal facial image is poorly explored. In this paper, we build an efficient and accurate system for simulating virtual teeth alignment effects in a frontal facial image. Our system takes a frontal face image of a patient with visible malpositioned teeth and the patient's 3D scanned teeth model as input, and progressively generates the visual results of the patient's teeth given the specific orthodontics planning steps from the doctor (i.e., the specification of translations and rotations of individual tooth). We design a multi-modal encoder-decoder based generative model to synthesize identity-preserving frontal facial images with aligned teeth. In addition, the original image color information is used to optimize the orthodontic outcomes, making the results more natural. We conduct extensive qualitative and clinical experiments and also a pilot study to validate our method.