HTR models development has become a conventional step for digital humanities projects. The performance of these models, often quite high, relies on manual transcription and numerous handwritten documents. Although the method has proven successful for Latin scripts, a similar amount of data is not yet achievable for scripts considered poorly-endowed, like Arabic scripts. In that respect, we are introducing and assessing a new modus operandi for HTR models development and fine-tuning dedicated to the Arabic Maghrib{\=i} scripts. The comparison between several state-of-the-art HTR demonstrates the relevance of a word-based neural approach specialized for Arabic, capable to achieve an error rate below 5% with only 10 pages manually transcribed. These results open new perspectives for Arabic scripts processing and more generally for poorly-endowed languages processing. This research is part of the development of RASAM dataset in partnership with the GIS MOMM and the BULAC.

View-dependent effects such as reflections pose a substantial challenge for image-based and neural rendering algorithms. Above all, curved reflectors are particularly hard, as they lead to highly non-linear reflection flows as the camera moves. We introduce a new point-based representation to compute Neural Point Catacaustics allowing novel-view synthesis of scenes with curved reflectors, from a set of casually-captured input photos. At the core of our method is a neural warp field that models catacaustic trajectories of reflections, so complex specular effects can be rendered using efficient point splatting in conjunction with a neural renderer. One of our key contributions is the explicit representation of reflections with a reflection point cloud which is displaced by the neural warp field, and a primary point cloud which is optimized to represent the rest of the scene. After a short manual annotation step, our approach allows interactive high-quality renderings of novel views with accurate reflection flow. Additionally, the explicit representation of reflection flow supports several forms of scene manipulation in captured scenes, such as reflection editing, cloning of specular objects, reflection tracking across views, and comfortable stereo viewing. We provide the source code and other supplemental material on https://repo-sam.inria.fr/ fungraph/neural_catacaustics/

Solute transport in porous media is relevant to a wide range of applications in hydrogeology, geothermal energy, underground CO2 storage, and a variety of chemical engineering systems. Due to the complexity of solute transport in heterogeneous porous media, traditional solvers require high resolution meshing and are therefore expensive computationally. This study explores the application of a mesh-free method based on deep learning to accelerate the simulation of solute transport. We employ Physics-informed Neural Networks (PiNN) to solve solute transport problems in homogeneous and heterogeneous porous media governed by the advection-dispersion equation. Unlike traditional neural networks that learn from large training datasets, PiNNs only leverage the strong form mathematical models to simultaneously solve for multiple dependent or independent field variables (e.g., pressure and solute concentration fields). In this study, we construct PiNN using a periodic activation function to better represent the complex physical signals (i.e., pressure) and their derivatives (i.e., velocity). Several case studies are designed with the intention of investigating the proposed PiNN's capability to handle different degrees of complexity. A manual hyperparameter tuning method is used to find the best PiNN architecture for each test case. Point-wise error and mean square error (MSE) measures are employed to assess the performance of PiNNs' predictions against the ground truth solutions obtained analytically or numerically using the finite element method. Our findings show that the predictions of PiNN are in good agreement with the ground truth solutions while reducing computational complexity and cost by, at least, three orders of magnitude.

Vulnerability to adversarial attacks is a well-known weakness of Deep Neural Networks. While most of the studies focus on natural images with standardized benchmarks like ImageNet and CIFAR, little research has considered real world applications, in particular in the medical domain. Our research shows that, contrary to previous claims, robustness of chest x-ray classification is much harder to evaluate and leads to very different assessments based on the dataset, the architecture and robustness metric. We argue that previous studies did not take into account the peculiarity of medical diagnosis, like the co-occurrence of diseases, the disagreement of labellers (domain experts), the threat model of the attacks and the risk implications for each successful attack. In this paper, we discuss the methodological foundations, review the pitfalls and best practices, and suggest new methodological considerations for evaluating the robustness of chest xray classification models. Our evaluation on 3 datasets, 7 models, and 18 diseases is the largest evaluation of robustness of chest x-ray classification models.

Lenia is a family of cellular automata (CA) generalizing Conway's Game of Life to continuous space, time and states. Lenia has attracted a lot of attention because of the wide diversity of self-organizing patterns it can generate. Among those, some spatially localized patterns (SLPs) resemble life-like artificial creatures. However, those creatures are found in only a small subspace of the Lenia parameter space and are not trivial to discover, necessitating advanced search algorithms. We hypothesize that adding a mass conservation constraint could facilitate the emergence of SLPs. We propose here an extension of the Lenia model, called Flow Lenia, which enables mass conservation. We show a few observations demonstrating its effectiveness in generating SLPs with complex behaviors. Furthermore, we show how Flow Lenia enables the integration of the parameters of the CA update rules within the CA dynamics, making them dynamic and localized. This allows for multi-species simulations, with locally coherent update rules that define properties of the emerging creatures, and that can be mixed with neighbouring rules. We argue that this paves the way for the intrinsic evolution of self-organized artificial life forms within continuous CAs.

Humans have been able to tackle biosphere complexities by acting as ecosystem engineers, profoundly changing the flows of matter, energy and information. This includes major innovations that allowed to reduce and control the impact of extreme events. Modelling the evolution of such adaptive dynamics can be challenging given the potentially large number of individual and environmental variables involved. This paper shows how to address this problem by using fire as the source of external, bursting and wide fluctuations. Fire propagates on a spatial landscape where a group of agents harvest and exploit trees while avoiding the damaging effects of fire spreading. The agents need to solve a conflict to reach a group-level optimal state: while tree harvesting reduces the propagation of fires, it also reduces the availability of resources provided by trees. It is shown that the system displays two major evolutionary innovations that end up in an ecological engineering strategy that favours high biomass along with the suppression of large fires. The implications for potential A.I. management of complex ecosystems are discussed.

We consider a model where a signal (discrete or continuous) is observed with an additive Gaussian noise process. The signal is issued from a linear combination of a finite but increasing number of translated features. The features are continuously parameterized by their location and depend on some scale parameter. First, we extend previous prediction results for off-the-grid estimators by taking into account here that the scale parameter may vary. The prediction bounds are analogous, but we improve the minimal distance between two consecutive features locations in order to achieve these bounds. Next, we propose a goodness-of-fit test for the model and give non-asymptotic upper bounds of the testing risk and of the minimax separation rate between two distinguishable signals. In particular, our test encompasses the signal detection framework. We deduce upper bounds on the minimal energy, expressed as the 2-norm of the linear coefficients, to successfully detect a signal in presence of noise. The general model considered in this paper is a non-linear extension of the classical high-dimensional regression model. It turns out that, in this framework, our upper bound on the minimax separation rate matches (up to a logarithmic factor) the lower bound on the minimax separation rate for signal detection in the high dimensional linear model associated to a fixed dictionary of features. We also propose a procedure to test whether the features of the observed signal belong to a given finite collection under the assumption that the linear coefficients may vary, but do not change to opposite signs under the null hypothesis. A non-asymptotic upper bound on the testing risk is given. We illustrate our results on the spikes deconvolution model with Gaussian features on the real line and with the Dirichlet kernel, frequently used in the compressed sensing literature, on the torus.

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two tasks using structural MRI. However, these methods often suffer from lack of interpretability, generalization, and can be limited in terms of performance. In this paper, we propose a novel deep framework designed to overcome these limitations. Our framework consists of two stages. In the first stage, we propose a deep grading model to extract meaningful features. To enhance the robustness of these features against domain shift, we introduce an innovative collective artificial intelligence strategy for training and evaluating steps. In the second stage, we use a graph convolutional neural network to better capture AD signatures. Our experiments based on 2074 subjects show the competitive performance of our deep framework compared to state-of-the-art methods on different datasets for both AD diagnosis and prognosis.

The emergence of COVID-19 has had a global and profound impact, not only on society as a whole, but also on the lives of individuals. Various prevention measures were introduced around the world to limit the transmission of the disease, including face masks, mandates for social distancing and regular disinfection in public spaces, and the use of screening applications. These developments also triggered the need for novel and improved computer vision techniques capable of (i) providing support to the prevention measures through an automated analysis of visual data, on the one hand, and (ii) facilitating normal operation of existing vision-based services, such as biometric authentication schemes, on the other. Especially important here, are computer vision techniques that focus on the analysis of people and faces in visual data and have been affected the most by the partial occlusions introduced by the mandates for facial masks. Such computer vision based human analysis techniques include face and face-mask detection approaches, face recognition techniques, crowd counting solutions, age and expression estimation procedures, models for detecting face-hand interactions and many others, and have seen considerable attention over recent years. The goal of this survey is to provide an introduction to the problems induced by COVID-19 into such research and to present a comprehensive review of the work done in the computer vision based human analysis field. Particular attention is paid to the impact of facial masks on the performance of various methods and recent solutions to mitigate this problem. Additionally, a detailed review of existing datasets useful for the development and evaluation of methods for COVID-19 related applications is also provided. Finally, to help advance the field further, a discussion on the main open challenges and future research direction is given.

To apply federated learning to drug discovery we developed a novel platform in the context of European Innovative Medicines Initiative (IMI) project MELLODDY (grant n{\deg}831472), which was comprised of 10 pharmaceutical companies, academic research labs, large industrial companies and startups. The MELLODDY platform was the first industry-scale platform to enable the creation of a global federated model for drug discovery without sharing the confidential data sets of the individual partners. The federated model was trained on the platform by aggregating the gradients of all contributing partners in a cryptographic, secure way following each training iteration. The platform was deployed on an Amazon Web Services (AWS) multi-account architecture running Kubernetes clusters in private subnets. Organisationally, the roles of the different partners were codified as different rights and permissions on the platform and administrated in a decentralized way. The MELLODDY platform generated new scientific discoveries which are described in a companion paper.