Contemporary methods have shown promising results on cardiac image segmentation, but merely in static learning, i.e., optimizing the network once for all, ignoring potential needs for model updating. In real-world scenarios, new data continues to be gathered from multiple institutions over time and new demands keep growing to pursue more satisfying performance. The desired model should incrementally learn from each incoming dataset and progressively update with improved functionality as time goes by. As the datasets sequentially delivered from multiple sites are normally heterogenous with domain discrepancy, each updated model should not catastrophically forget previously learned domains while well generalizing to currently arrived domains or even unseen domains. In medical scenarios, this is particularly challenging as accessing or storing past data is commonly not allowed due to data privacy. To this end, we propose a novel domain-incremental learning framework to recover past domain inputs first and then regularly replay them during model optimization. Particularly, we first present a style-oriented replay module to enable structure-realistic and memory-efficient reproduction of past data, and then incorporate the replayed past data to jointly optimize the model with current data to alleviate catastrophic forgetting. During optimization, we additionally perform domain-sensitive feature whitening to suppress model's dependency on features that are sensitive to domain changes (e.g., domain-distinctive style features) to assist domain-invariant feature exploration and gradually improve the generalization performance of the network. We have extensively evaluated our approach with the M&Ms Dataset in single-domain and compound-domain incremental learning settings with improved performance over other comparison approaches.

人类的持续学习（CL）能力与稳定性与可塑性困境密切相关，描述了人类如何实现持续的学习能力和保存的学习信息。自发育以来，CL的概念始终存在于人工智能（AI）中。本文提出了对CL的全面审查。与之前的评论不同，主要关注CL中的灾难性遗忘现象，本文根据稳定性与可塑性机制的宏观视角来调查CL。类似于生物对应物，“智能”AI代理商应该是I）记住以前学到的信息（信息回流）; ii）不断推断新信息（信息浏览:); iii）转移有用的信息（信息转移），以实现高级CL。根据分类学，评估度量，算法，应用以及一些打开问题。我们的主要贡献涉及I）从人工综合情报层面重新检查CL; ii）在CL主题提供详细和广泛的概述; iii）提出一些关于CL潜在发展的新颖思路。

Deep learning models can achieve high accuracy when trained on large amounts of labeled data. However, real-world scenarios often involve several challenges: Training data may become available in installments, may originate from multiple different domains, and may not contain labels for training. Certain settings, for instance medical applications, often involve further restrictions that prohibit retention of previously seen data due to privacy regulations. In this work, to address such challenges, we study unsupervised segmentation in continual learning scenarios that involve domain shift. To that end, we introduce GarDA (Generative Appearance Replay for continual Domain Adaptation), a generative-replay based approach that can adapt a segmentation model sequentially to new domains with unlabeled data. In contrast to single-step unsupervised domain adaptation (UDA), continual adaptation to a sequence of domains enables leveraging and consolidation of information from multiple domains. Unlike previous approaches in incremental UDA, our method does not require access to previously seen data, making it applicable in many practical scenarios. We evaluate GarDA on two datasets with different organs and modalities, where it substantially outperforms existing techniques.

Continual Learning (CL) is a field dedicated to devise algorithms able to achieve lifelong learning. Overcoming the knowledge disruption of previously acquired concepts, a drawback affecting deep learning models and that goes by the name of catastrophic forgetting, is a hard challenge. Currently, deep learning methods can attain impressive results when the data modeled does not undergo a considerable distributional shift in subsequent learning sessions, but whenever we expose such systems to this incremental setting, performance drop very quickly. Overcoming this limitation is fundamental as it would allow us to build truly intelligent systems showing stability and plasticity. Secondly, it would allow us to overcome the onerous limitation of retraining these architectures from scratch with the new updated data. In this thesis, we tackle the problem from multiple directions. In a first study, we show that in rehearsal-based techniques (systems that use memory buffer), the quantity of data stored in the rehearsal buffer is a more important factor over the quality of the data. Secondly, we propose one of the early works of incremental learning on ViTs architectures, comparing functional, weight and attention regularization approaches and propose effective novel a novel asymmetric loss. At the end we conclude with a study on pretraining and how it affects the performance in Continual Learning, raising some questions about the effective progression of the field. We then conclude with some future directions and closing remarks.

Artificial neural networks thrive in solving the classification problem for a particular rigid task, acquiring knowledge through generalized learning behaviour from a distinct training phase. The resulting network resembles a static entity of knowledge, with endeavours to extend this knowledge without targeting the original task resulting in a catastrophic forgetting. Continual learning shifts this paradigm towards networks that can continually accumulate knowledge over different tasks without the need to retrain from scratch. We focus on task incremental classification, where tasks arrive sequentially and are delineated by clear boundaries. Our main contributions concern (1) a taxonomy and extensive overview of the state-of-the-art; (2) a novel framework to continually determine the stability-plasticity trade-off of the continual learner; (3) a comprehensive experimental comparison of 11 state-of-the-art continual learning methods and 4 baselines. We empirically scrutinize method strengths and weaknesses on three benchmarks, considering Tiny Imagenet and large-scale unbalanced iNaturalist and a sequence of recognition datasets. We study the influence of model capacity, weight decay and dropout regularization, and the order in which the tasks are presented, and qualitatively compare methods in terms of required memory, computation time and storage.

人类智慧的主食是以不断的方式获取知识的能力。在Stark对比度下，深网络忘记灾难性，而且为此原因，类增量连续学习促进方法的子字段逐步学习一系列任务，将顺序获得的知识混合成综合预测。这项工作旨在评估和克服我们以前提案黑暗体验重播（Der）的陷阱，这是一种简单有效的方法，将排练和知识蒸馏结合在一起。灵感来自于我们的思想不断重写过去的回忆和对未来的期望，我们赋予了我的能力，即我的能力来修改其重播记忆，以欢迎有关过去数据II的新信息II）为学习尚未公开的课程铺平了道路。我们表明，这些策略的应用导致了显着的改进;实际上，得到的方法 - 被称为扩展-DAR（X-DER） - 优于标准基准（如CiFar-100和MiniimAgeNet）的技术状态，并且这里引入了一个新颖的。为了更好地了解，我们进一步提供了广泛的消融研究，以证实并扩展了我们以前研究的结果（例如，在持续学习设置中知识蒸馏和漂流最小值的价值）。

小儿肌肉骨骼系统的临床诊断依赖于医学成像检查的分析。在医学图像处理管道中，使用深度学习算法的语义分割使人可以自动生成患者特定的三维解剖模型，这对于形态学评估至关重要。但是，小儿成像资源的稀缺性可能导致单个深层分割模型的准确性和泛化性能降低。在这项研究中，我们建议设计一个新型的多任务多任务多域学习框架，在该框架中，单个分割网络对由解剖学的不同部分产生的多个数据集进行了优化。与以前的方法不同，我们同时考虑多个强度域和分割任务来克服小儿数据的固有稀缺性，同时利用成像数据集之间的共享特征。为了进一步提高概括能力，我们从自然图像分类中采用了转移学习方案，以及旨在在共享表示中促进域特异性群集的多尺度对比正则化，以及多连接解剖学先验来执行解剖学上一致的预测。我们评估了使用脚踝，膝盖和肩关节的三个稀缺和小儿成像数据集进行骨分割的贡献。我们的结果表明，所提出的方法在骰子指标中的表现优于个人，转移和共享分割方案，并具有统计学上足够的利润。拟议的模型为智能使用成像资源和更好地管理小儿肌肉骨骼疾病提供了新的观点。

最近已经为医疗图像分割任务创建了许多医疗数据集，并且自然质疑我们是否可以使用它们来依次训练（1）在所有这些数据集中表现更好的单个模型，并且（2）良好的概括和传输更好到未知的目标站点域。先前的工作通过在多站点数据集上共同训练一个模型来实现这一目标，该模型平均实现了竞争性能，但是这种方法依赖于所有培训数据的可用性的假设，从而限制了其在实际部署中的有效性。在本文中，我们提出了一个称为增量转移学习（ITL）的新型多站点分割框架，该框架以端到端的顺序方式从多站点数据集中学习模型。具体而言，“增量”是指顺序构建的数据集，而“转移”是通过利用每个数据集上嵌入功能的线性组合的有用信息来实现的。此外，我们介绍了ITL框架，在该框架中，我们在其中训练网络，包括具有预先训练的权重和最多两个分段解码器头的站点不合时宜的编码器。我们还设计了一种新型的站点级增量损失，以便在目标域上良好地概括。其次，我们首次表明利用我们的ITL培训计划能够减轻富有灾难性的遗忘问题，从而在渐进学习中遇到了挑战。我们使用五个具有挑战性的基准数据集进行实验，以验证我们的增量转移学习方法的有效性。我们的方法对计算资源和特定于领域的专业知识的假设最少，因此构成了多站点医学图像细分的强大起点。

Attempts to train a comprehensive artificial intelligence capable of solving multiple tasks have been impeded by a chronic problem called catastrophic forgetting.Although simply replaying all previous data alleviates the problem, it requires large memory and even worse, often infeasible in real world applications where the access to past data is limited. Inspired by the generative nature of the hippocampus as a short-term memory system in primate brain, we propose the Deep Generative Replay, a novel framework with a cooperative dual model architecture consisting of a deep generative model ("generator") and a task solving model ("solver"). With only these two models, training data for previous tasks can easily be sampled and interleaved with those for a new task. We test our methods in several sequential learning settings involving image classification tasks.

Neural networks are prone to catastrophic forgetting when trained incrementally on different tasks. Popular incremental learning methods mitigate such forgetting by retaining a subset of previously seen samples and replaying them during the training on subsequent tasks. However, this is not always possible, e.g., due to data protection regulations. In such restricted scenarios, one can employ generative models to replay either artificial images or hidden features to a classifier. In this work, we propose Genifer (GENeratIve FEature-driven image Replay), where a generative model is trained to replay images that must induce the same hidden features as real samples when they are passed through the classifier. Our technique therefore incorporates the benefits of both image and feature replay, i.e.: (1) unlike conventional image replay, our generative model explicitly learns the distribution of features that are relevant for classification; (2) in contrast to feature replay, our entire classifier remains trainable; and (3) we can leverage image-space augmentations, which increase distillation performance while also mitigating overfitting during the training of the generative model. We show that Genifer substantially outperforms the previous state of the art for various settings on the CIFAR-100 and CUB-200 datasets.

在过去的十年中，许多深入学习模型都受到了良好的培训，并在各种机器智能领域取得了巨大成功，特别是对于计算机视觉和自然语言处理。为了更好地利用这些训练有素的模型在域内或跨域转移学习情况下，提出了知识蒸馏（KD）和域适应（DA）并成为研究亮点。他们旨在通过原始培训数据从训练有素的模型转移有用的信息。但是，由于隐私，版权或机密性，原始数据并不总是可用的。最近，无数据知识转移范式吸引了吸引人的关注，因为它涉及从训练有素的模型中蒸馏宝贵的知识，而无需访问培训数据。特别是，它主要包括无数据知识蒸馏（DFKD）和源无数据域适应（SFDA）。一方面，DFKD旨在将域名域内知识从一个麻烦的教师网络转移到一个紧凑的学生网络，以进行模型压缩和有效推论。另一方面，SFDA的目标是重用存储在训练有素的源模型中的跨域知识并将其调整为目标域。在本文中，我们对知识蒸馏和无监督域适应的视角提供了全面的数据知识转移，以帮助读者更好地了解目前的研究状况和想法。分别简要审查了这两个领域的应用和挑战。此外，我们对未来研究的主题提供了一些见解。

持续学习旨在快速，不断地从一系列任务中学习当前的任务。与其他类型的方法相比，基于经验重播的方法表现出了极大的优势来克服灾难性的遗忘。该方法的一个常见局限性是上一个任务和当前任务之间的数据不平衡，这将进一步加剧遗忘。此外，如何在这种情况下有效解决稳定性困境也是一个紧迫的问题。在本文中，我们通过提出一个通过多尺度知识蒸馏和数据扩展（MMKDDA）提出一个名为Meta学习更新的新框架来克服这些挑战。具体而言，我们应用多尺度知识蒸馏来掌握不同特征级别的远程和短期空间关系的演变，以减轻数据不平衡问题。此外，我们的方法在在线持续训练程序中混合了来自情节记忆和当前任务的样品，从而减轻了由于概率分布的变化而减轻了侧面影响。此外，我们通过元学习更新来优化我们的模型，该更新诉诸于前面所看到的任务数量，这有助于保持稳定性和可塑性之间的更好平衡。最后，我们对四个基准数据集的实验评估显示了提出的MMKDDA框架对其他流行基线的有效性，并且还进行了消融研究，以进一步分析每个组件在我们的框架中的作用。

基于深度学习的计算机辅助诊断（CAD）在学术研究和临床应用中引起了吸引人的关注。然而，卷积神经网络（CNN）诊断系统严重依赖于标记的病变数据集，对数据分布变化的敏感性也限制了CNN在CAD中的潜在应用。开发了无监督的域适应性（UDA）方法来解决昂贵的注释和域间隙问题，并在医学图像分析中取得了巨大的成功。然而，现有的UDA方法仅适应从源病变域中汲取的知识到一个单个目标病变域，这是针对临床情况的：要诊断的新的未标记的目标域始终以在线和连续的方式到达。此外，由于新知识的知识覆盖了先前学到的知识（即灾难性的遗忘），因此现有方法的性能在先前学到的目标病变域上大大降低。为了处理上述问题，我们开发了一个名为连续病变知识元适应（CLKM）的元适应框架，该框架主要由语义适应阶段（​​SAP）和表示适应阶段（​​RAP）组成，以在线学习诊断模型和连续的方式。在SAP中，从源病变域中学到的语义知识转移到连续的靶病变域。在RAP中，优化了功能提取器以对齐整个源和多个目标病变域的可转移表示知识。

恶意软件（恶意软件）分类为持续学习（CL）制度提供了独特的挑战，这是由于每天收到的新样本的数量以及恶意软件的发展以利用新漏洞。在典型的一天中，防病毒供应商将获得数十万个独特的软件，包括恶意和良性，并且在恶意软件分类器的一生中，有超过十亿个样品很容易积累。鉴于问题的规模，使用持续学习技术的顺序培训可以在减少培训和存储开销方面提供可观的好处。但是，迄今为止，还没有对CL应用于恶意软件分类任务的探索。在本文中，我们研究了11种应用于三个恶意软件任务的CL技术，涵盖了常见的增量学习方案，包括任务，类和域增量学习（IL）。具体而言，使用两个现实的大规模恶意软件数据集，我们评估了CL方法在二进制恶意软件分类（domain-il）和多类恶意软件家庭分类（Task-IL和类IL）任务上的性能。令我们惊讶的是，在几乎所有情况下，持续的学习方法显着不足以使训练数据的幼稚关节重播 - 在某些情况下，将精度降低了70个百分点以上。与关节重播相比，有选择性重播20％的存储数据的一种简单方法可以实现更好的性能，占训练时间的50％。最后，我们讨论了CL技术表现出乎意料差的潜在原因，希望它激发进一步研究在恶意软件分类域中更有效的技术。

随着生成对冲网络（GANS）的快速进步，综合场景的视觉质量不断改进，包括复杂的城市场景，其中包含自动驾驶的应用。我们在这项工作中解决了一个持续的场景生成设置，其中GAN在不同的域流上培训;理想情况下，学习的模型最终应该能够在所有看到的域中生成新场景。此设置反映了现实生活场景，其中数据在不同时间的不同地方不断获取。在这种持续的设置中，我们的目标是学习零遗忘，即，由于灾难性的遗忘，在早期域内没有综合质量下降。为此，我们介绍了一种新颖的框架，不仅（i）可以在持续培训中实现无缝知识转移，而且（ii）还能以小的开销成本保证零遗忘。虽然更加内存有效，但由于继续学习，我们的模型比较每个域为一个完整模型的蛮力解决方案比较了更好的合成质量。特别是，在极端的低数据制度下，我们的方法通过大幅度大幅优于蛮力。

While deep learning methods hitherto have achieved considerable success in medical image segmentation, they are still hampered by two limitations: (i) reliance on large-scale well-labeled datasets, which are difficult to curate due to the expert-driven and time-consuming nature of pixel-level annotations in clinical practices, and (ii) failure to generalize from one domain to another, especially when the target domain is a different modality with severe domain shifts. Recent unsupervised domain adaptation~(UDA) techniques leverage abundant labeled source data together with unlabeled target data to reduce the domain gap, but these methods degrade significantly with limited source annotations. In this study, we address this underexplored UDA problem, investigating a challenging but valuable realistic scenario, where the source domain not only exhibits domain shift~w.r.t. the target domain but also suffers from label scarcity. In this regard, we propose a novel and generic framework called ``Label-Efficient Unsupervised Domain Adaptation"~(LE-UDA). In LE-UDA, we construct self-ensembling consistency for knowledge transfer between both domains, as well as a self-ensembling adversarial learning module to achieve better feature alignment for UDA. To assess the effectiveness of our method, we conduct extensive experiments on two different tasks for cross-modality segmentation between MRI and CT images. Experimental results demonstrate that the proposed LE-UDA can efficiently leverage limited source labels to improve cross-domain segmentation performance, outperforming state-of-the-art UDA approaches in the literature. Code is available at: https://github.com/jacobzhaoziyuan/LE-UDA.

Continual Learning is a step towards lifelong intelligence where models continuously learn from recently collected data without forgetting previous knowledge. Existing continual learning approaches mostly focus on image classification in the class-incremental setup with clear task boundaries and unlimited computational budget. This work explores Online Domain-Incremental Continual Segmentation~(ODICS), a real-world problem that arises in many applications, \eg, autonomous driving. In ODICS, the model is continually presented with batches of densely labeled images from different domains; computation is limited and no information about the task boundaries is available. In autonomous driving, this may correspond to the realistic scenario of training a segmentation model over time on a sequence of cities. We analyze several existing continual learning methods and show that they do not perform well in this setting despite working well in class-incremental segmentation. We propose SimCS, a parameter-free method complementary to existing ones that leverages simulated data as a continual learning regularizer. Extensive experiments show consistent improvements over different types of continual learning methods that use regularizers and even replay.

我们在本文中解决了增量无监督域适应（IDA）的新问题。我们假设标记的源域和不同的未标记的目标域通过约束逐步观察到与当前域的数据仅一次可用。目标是为当前域概括为所有过去域的准确性。 IDA设置因域之间的突然差异以及包括源域内的过去数据的不可用。受到生成功能重放的概念的启发，我们提出了一种名为特征重放的增量域适应（Frida）的新颖框架，它利用了一个名为域 - 通用辅助分类GaN（DGAC-GaN）的新的增量生成对抗性网络（GAN）来生产域明确的特征表示无缝。对于域对齐，我们提出了一种简单的扩展名为Dann-Ib的流行域对抗神经网络（Dann），鼓励歧视域 - 不变和任务相关的特征学习。 Office-Home，Office-Caltech和Domainnet数据集的实验结果证实，FIDA维护了卓越的稳定性可塑性权衡，而不是文献。

Graph learning is a popular approach for performing machine learning on graph-structured data. It has revolutionized the machine learning ability to model graph data to address downstream tasks. Its application is wide due to the availability of graph data ranging from all types of networks to information systems. Most graph learning methods assume that the graph is static and its complete structure is known during training. This limits their applicability since they cannot be applied to problems where the underlying graph grows over time and/or new tasks emerge incrementally. Such applications require a lifelong learning approach that can learn the graph continuously and accommodate new information whilst retaining previously learned knowledge. Lifelong learning methods that enable continuous learning in regular domains like images and text cannot be directly applied to continuously evolving graph data, due to its irregular structure. As a result, graph lifelong learning is gaining attention from the research community. This survey paper provides a comprehensive overview of recent advancements in graph lifelong learning, including the categorization of existing methods, and the discussions of potential applications and open research problems.

持续学习旨在通过以在线学习方式利用过去获得的知识，同时能够在所有以前的任务上表现良好，从而学习一系列任务，这对人工智能（AI）系统至关重要，因此持续学习与传统学习模式相比，更适合大多数现实和复杂的应用方案。但是，当前的模型通常在每个任务上的类标签上学习一个通用表示基础，并选择有效的策略来避免灾难性的遗忘。我们假设，仅从获得的知识中选择相关且有用的零件比利用整个知识更有效。基于这一事实，在本文中，我们提出了一个新框架，名为“选择相关的在线持续学习知识（SRKOCL），该框架结合了一种额外的有效频道注意机制，以选择每个任务的特定相关知识。我们的模型还结合了经验重播和知识蒸馏，以避免灾难性的遗忘。最后，在不同的基准上进行了广泛的实验，竞争性实验结果表明，我们提出的SRKOCL是针对最先进的承诺方法。