组织病理学图像合成的现有深网无法为聚类核生成准确的边界,并且无法输出与不同器官一致的图像样式。为了解决这些问题,我们提出了一种样式引导的实例自适应标准化(SIAN),以合成不同器官的逼真的颜色分布和纹理。 Sian包含四个阶段:语义,风格化,实例化和调制。这四个阶段共同起作用,并集成到生成网络中,以嵌入图像语义,样式和实例级级边界。实验结果证明了所有组件在Sian中的有效性,并表明所提出的方法比使用Frechet Inception Inception距离(FID),结构相似性指数(SSIM),检测质量胜过组织病理学图像合成的最新条件gan。 (DQ),分割质量(SQ)和圆锥体质量(PQ)。此外,通过合并使用Sian产生的合成图像,可以显着改善分割网络的性能。
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We propose semantic region-adaptive normalization (SEAN), a simple but effective building block for Generative Adversarial Networks conditioned on segmentation masks that describe the semantic regions in the desired output image. Using SEAN normalization, we can build a network architecture that can control the style of each semantic region individually, e.g., we can specify one style reference image per region. SEAN is better suited to encode, transfer, and synthesize style than the best previous method in terms of reconstruction quality, variability, and visual quality. We evaluate SEAN on multiple datasets and report better quan-titative metrics (e.g. FID, PSNR) than the current state of the art. SEAN also pushes the frontier of interactive image editing. We can interactively edit images by changing segmentation masks or the style for any given region. We can also interpolate styles from two reference images per region. Code: https://github.com/ZPdesu/SEAN .
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语义图像编辑利用本地语义标签图来生成所需的内容。最近的工作借用了Spade Block来实现语义图像编辑。但是,由于编辑区域和周围像素之间的样式差异,它无法产生令人愉悦的结果。我们将其归因于以下事实:Spade仅使用与图像无关的局部语义布局,但忽略了已知像素中包含的图像特定样式。为了解决此问题,我们提出了一个样式保存的调制(SPM),其中包括两个调制过程:第一个调制包含上下文样式和语义布局,然后生成两个融合的调制参数。第二次调制采用融合参数来调制特征图。通过使用这两种调制,SPM可以在保留特定图像的上下文样式的同时注入给定的语义布局。此外,我们设计了一种渐进式体系结构,以粗到精细的方式生成编辑的内容。提出的方法可以获得上下文一致的结果,并显着减轻生成区域和已知像素之间的不愉快边界。
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Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In this work, we propose a novel framework called SynCLay (Synthesis from Cellular Layouts) that can construct realistic and high-quality histology images from user-defined cellular layouts along with annotated cellular boundaries. Tissue image generation based on bespoke cellular layouts through the proposed framework allows users to generate different histological patterns from arbitrary topological arrangement of different types of cells. SynCLay generated synthetic images can be helpful in studying the role of different types of cells present in the tumor microenvironmet. Additionally, they can assist in balancing the distribution of cellular counts in tissue images for designing accurate cellular composition predictors by minimizing the effects of data imbalance. We train SynCLay in an adversarial manner and integrate a nuclear segmentation and classification model in its training to refine nuclear structures and generate nuclear masks in conjunction with synthetic images. During inference, we combine the model with another parametric model for generating colon images and associated cellular counts as annotations given the grade of differentiation and cell densities of different cells. We assess the generated images quantitatively and report on feedback from trained pathologists who assigned realism scores to a set of images generated by the framework. The average realism score across all pathologists for synthetic images was as high as that for the real images. We also show that augmenting limited real data with the synthetic data generated by our framework can significantly boost prediction performance of the cellular composition prediction task.
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图像合成的现有方法利用基于堆叠的堆叠和池层的样式编码器,以从输入图像生成样式代码。然而,编码的矢量不一定包含相应图像的本地信息,因为通过这种缩小程序往往将小规模对象倾向于“撤离”。在本文中,我们提出了基于Superpixel的式编码器的深度图像合成,名为SuperstyLeNet。首先,我们基于SuperPixels直接从原始图像中提取样式代码,以考虑本地对象。其次,基于图形分析,我们在矢量化风格代码中恢复空间关系。因此,所提出的网络通过将样式代码映射到语义标签来实现高质量的图像合成。实验结果表明,该方法在视觉质量和定量测量方面优于最先进的方法。此外,我们通过调整样式代码来实现精心制作的空间方式编辑。
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组织病理学分析是对癌前病变诊断的本金标准。从数字图像自动组织病理学分类的目标需要监督培训,这需要大量的专家注释,这可能是昂贵且耗时的收集。同时,精确分类从全幻灯片裁剪的图像斑块对于基于标准滑动窗口的组织病理学幻灯片分类方法是必不可少的。为了减轻这些问题,我们提出了一个精心设计的条件GaN模型,即hostogan,用于在类标签上合成现实组织病理学图像补丁。我们还研究了一种新颖的合成增强框架,可选择地添加由我们提出的HADOGAN生成的新的合成图像补丁,而不是直接扩展与合成图像的训练集。通过基于其指定标签的置信度和实际标记图像的特征相似性选择合成图像,我们的框架为合成增强提供了质量保证。我们的模型在两个数据集上进行评估:具有有限注释的宫颈组织病理学图像数据集,以及具有转移性癌症的淋巴结组织病理学图像的另一个数据集。在这里,我们表明利用具有选择性增强的组织产生的图像导致对宫颈组织病理学和转移性癌症数据集分别的分类性能(分别为6.7%和2.8%)的显着和一致性。
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Generative models have been very successful over the years and have received significant attention for synthetic data generation. As deep learning models are getting more and more complex, they require large amounts of data to perform accurately. In medical image analysis, such generative models play a crucial role as the available data is limited due to challenges related to data privacy, lack of data diversity, or uneven data distributions. In this paper, we present a method to generate brain tumor MRI images using generative adversarial networks. We have utilized StyleGAN2 with ADA methodology to generate high-quality brain MRI with tumors while using a significantly smaller amount of training data when compared to the existing approaches. We use three pre-trained models for transfer learning. Results demonstrate that the proposed method can learn the distributions of brain tumors. Furthermore, the model can generate high-quality synthetic brain MRI with a tumor that can limit the small sample size issues. The approach can addresses the limited data availability by generating realistic-looking brain MRI with tumors. The code is available at: ~\url{https://github.com/rizwanqureshi123/Brain-Tumor-Synthetic-Data}.
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交换自动编码器在深层图像操纵和图像到图像翻译中实现了最先进的性能。我们通过基于梯度逆转层引入简单而有效的辅助模块来改善这项工作。辅助模块的损失迫使发电机学会使用全零纹理代码重建图像,从而鼓励结构和纹理信息之间更好地分解。提出的基于属性的转移方法可以在样式传输中进行精致的控制,同时在不使用语义掩码的情况下保留结构信息。为了操纵图像,我们将对象的几何形状和输入图像的一般样式编码为两个潜在代码,并具有实施结构一致性的附加约束。此外,由于辅助损失,训练时间大大减少。提出的模型的优越性在复杂的域中得到了证明,例如已知最先进的卫星图像。最后,我们表明我们的模型改善了广泛的数据集的质量指标,同时通过多模式图像生成技术实现了可比的结果。
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近年来,由于其在图像生成过程中的可控性,有条件的图像合成引起了不断的关注。虽然最近的作品取得了现实的结果,但大多数都没有处理细微细节的细粒度风格。为了解决这个问题,提出了一种名为DRAN的新型归一化模块。它学会了细粒度的风格表示,同时保持普通风格的稳健性。具体来说,我们首先引入多级结构,空间感知金字塔汇集,以指导模型学习粗略的功能。然后,为了自适应地保险熔断不同的款式,我们提出动态门控,使得可以根据不同的空间区域选择不同的样式。为了评估DRAN的有效性和泛化能力,我们对化妆和语义图像合成进行了一组实验。定量和定性实验表明,配备了DRAN,基线模型能够实现复杂风格转移和纹理细节重建的显着改善。
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最近的研究表明,风格老年提供了对图像合成和编辑的下游任务的有希望的现有模型。然而,由于样式盖的潜在代码被设计为控制全球样式,因此很难实现对合成图像的细粒度控制。我们提出了SemanticStylegan,其中发电机训练以分别培训局部语义部件,并以组成方式合成图像。不同局部部件的结构和纹理由相应的潜在码控制。实验结果表明,我们的模型在不同空间区域之间提供了强烈的解剖。当与为样式器设计的编辑方法结合使用时,它可以实现更细粒度的控制,以编辑合成或真实图像。该模型也可以通过传输学习扩展到其他域。因此,作为具有内置解剖学的通用先前模型,它可以促进基于GaN的应用的发展并实现更多潜在的下游任务。
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我们通过将此任务视为视觉令牌生成问题来提出新的视角来实现图像综合。与现有的范例不同,即直接从单个输入(例如,潜像)直接合成完整图像,新配方使得能够为不同的图像区域进行灵活的本地操作,这使得可以学习内容感知和细粒度的样式控制用于图像合成。具体地,它需要输入潜像令牌的序列,以预测用于合成图像的视觉令牌。在这种观点来看,我们提出了一个基于令牌的发电机(即Tokengan)。特别是,Tokengan输入了两个语义不同的视觉令牌,即,来自潜在空间的学习常量内容令牌和风格代币。鉴于一系列风格令牌,Tokengan能够通过用变压器将样式分配给内容令牌来控制图像合成。我们进行了广泛的实验,并表明拟议的Tokengan在几个广泛使用的图像综合基准上实现了最先进的结果,包括FFHQ和LSUN教会,具有不同的决议。特别地,发电机能够用1024x1024尺寸合成高保真图像,完全用卷曲分配。
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Current state-of-the-art segmentation techniques for ocular images are critically dependent on large-scale annotated datasets, which are labor-intensive to gather and often raise privacy concerns. In this paper, we present a novel framework, called BiOcularGAN, capable of generating synthetic large-scale datasets of photorealistic (visible light and near-infrared) ocular images, together with corresponding segmentation labels to address these issues. At its core, the framework relies on a novel Dual-Branch StyleGAN2 (DB-StyleGAN2) model that facilitates bimodal image generation, and a Semantic Mask Generator (SMG) component that produces semantic annotations by exploiting latent features of the DB-StyleGAN2 model. We evaluate BiOcularGAN through extensive experiments across five diverse ocular datasets and analyze the effects of bimodal data generation on image quality and the produced annotations. Our experimental results show that BiOcularGAN is able to produce high-quality matching bimodal images and annotations (with minimal manual intervention) that can be used to train highly competitive (deep) segmentation models (in a privacy aware-manner) that perform well across multiple real-world datasets. The source code for the BiOcularGAN framework is publicly available at https://github.com/dariant/BiOcularGAN.
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将带家具的房间图像转换为背景的任务 - 仅是非常具有挑战性,因为它需要在仍然保持整体布局和风格的同时进行大量变化。为了获得照片 - 现实和结构一致的背景,现有的深度学习方法使用图像修复方法或将场景布局的学习作为个人任务,以后在不完全可分辨率的语义区域自适应归一代化模块中利用它。为了解决这些缺点,我们将场景布局生成视为特征线性变换问题,并提出了一个简单但有效的调整后的完全可分辨率的软语义区域 - 自适应归一化模块(SoftSean)块。我们展示了现实和深度估计任务的缩短和深度估计任务中的适用性,在那里我们的方法除了减轻培训复杂性和不可差异性问题的优点,超越了定量和定性的比较方法。我们的SoftSean块可用作现有辨别和生成模型的液位模块。在vcl3d.github.io/panodr/上提供实现。
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提供和渲染室内场景一直是室内设计的一项长期任务,艺术家为空间创建概念设计,建立3D模型的空间,装饰,然后执行渲染。尽管任务很重要,但它很乏味,需要巨大的努力。在本文中,我们引入了一个特定领域的室内场景图像合成的新问题,即神经场景装饰。鉴于一张空的室内空间的照片以及用户确定的布局列表,我们旨在合成具有所需的家具和装饰的相同空间的新图像。神经场景装饰可用于以简单而有效的方式创建概念室内设计。我们解决这个研究问题的尝试是一种新颖的场景生成体系结构,它将空的场景和对象布局转化为现实的场景照片。我们通过将其与有条件图像合成基线进行比较,以定性和定量的方式将其进行比较,证明了我们提出的方法的性能。我们进行广泛的实验,以进一步验证我们生成的场景的合理性和美学。我们的实现可在\ url {https://github.com/hkust-vgd/neural_scene_decoration}获得。
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胸部X射线(CXR)图像中的肺结节检测是肺癌的早期筛查。基于深度学习的计算机辅助诊断(CAD)系统可以支持放射线医生在CXR中进行结节筛选。但是,它需要具有高质量注释的大规模和多样化的医学数据,以训练这种强大而准确的CAD。为了减轻此类数据集的有限可用性,为了增加数据增强而提出了肺结核合成方法。然而,以前的方法缺乏产生结节的能力,这些结节与检测器所需的大小属性相关。为了解决这个问题,我们在本文中介绍了一种新颖的肺结综合框架,该框架分别将结节属性分为三个主要方面,包括形状,大小和纹理。基于GAN的形状生成器首先通过产生各种形状掩模来建模结节形状。然后,以下大小调制可以对像素级粒度中生成的结节形状的直径进行定量控制。一条粗到细门的卷积卷积纹理发生器最终合成了以调制形状掩模为条件的视觉上合理的结节纹理。此外,我们建议通过控制数据增强的分离结节属性来合成结节CXR图像,以便更好地补偿检测任务中容易错过的结节。我们的实验证明了所提出的肺结构合成框架的图像质量,多样性和可控性的增强。我们还验证了数据增强对大大改善结节检测性能的有效性。
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已显示自动深度学习分割模型可提高分割效率和准确性。但是,训练强大的分割模型需要大量标记的训练样本,这可能是不切实际的。这项研究旨在开发一个深度学习框架,用于生成可用于增强网络培训的合成病变。病变合成网络是一种修改的生成对抗网络(GAN)。具体而言,我们创新了部分卷积策略来构建一个类似于Unet的发电机。该鉴别器是使用具有梯度惩罚和光谱归一化的Wasserstein GAN设计的。开发了基于主成分分析的掩模生成方法,以模拟各种病变形状。然后通过病变合成网络将生成的面膜转换为肝病。评估了病变的合成框架的病变纹理,并使用合成病变来训练病变分割网络,以进一步验证该框架的有效性。所有网络均经过LIT的公共数据集训练和测试。与所采用的两个纹理参数(GLCM-能量和GLCM相关)相比,该方法产生的合成病变具有非常相似的直方图分布。 GLCM-能量和GlCM相关的Kullback-Lebler差异分别为0.01和0.10。包括肿瘤分割网络中的合成病变包括U-NET的分割骰子性能从67.3%显着提高到71.4%(p <0.05)。同时,体积的精度和灵敏度从74.6%提高到76.0%(p = 0.23)和66.1%至70.9%(p <0.01)。合成数据可显着提高分割性能。
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Structure-guided image completion aims to inpaint a local region of an image according to an input guidance map from users. While such a task enables many practical applications for interactive editing, existing methods often struggle to hallucinate realistic object instances in complex natural scenes. Such a limitation is partially due to the lack of semantic-level constraints inside the hole region as well as the lack of a mechanism to enforce realistic object generation. In this work, we propose a learning paradigm that consists of semantic discriminators and object-level discriminators for improving the generation of complex semantics and objects. Specifically, the semantic discriminators leverage pretrained visual features to improve the realism of the generated visual concepts. Moreover, the object-level discriminators take aligned instances as inputs to enforce the realism of individual objects. Our proposed scheme significantly improves the generation quality and achieves state-of-the-art results on various tasks, including segmentation-guided completion, edge-guided manipulation and panoptically-guided manipulation on Places2 datasets. Furthermore, our trained model is flexible and can support multiple editing use cases, such as object insertion, replacement, removal and standard inpainting. In particular, our trained model combined with a novel automatic image completion pipeline achieves state-of-the-art results on the standard inpainting task.
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Facial image manipulation has achieved great progress in recent years. However, previous methods either operate on a predefined set of face attributes or leave users little freedom to interactively manipulate images. To overcome these drawbacks, we propose a novel framework termed MaskGAN, enabling diverse and interactive face manipulation. Our key insight is that semantic masks serve as a suitable intermediate representation for flexible face manipulation with fidelity preservation. MaskGAN has two main components: 1) Dense Mapping Network (DMN) and 2) Editing Behavior Simulated Training (EBST). Specifically, DMN learns style mapping between a free-form user modified mask and a target image, enabling diverse generation results. EBST models the user editing behavior on the source mask, making the overall framework more robust to various manipulated inputs. Specifically, it introduces dual-editing consistency as the auxiliary supervision signal. To facilitate extensive studies, we construct a large-scale high-resolution face dataset with fine-grained mask annotations named CelebAMask-HQ. MaskGAN is comprehensively evaluated on two challenging tasks: attribute transfer and style copy, demonstrating superior performance over other state-of-the-art methods. The code, models, and dataset are available at https://github.com/switchablenorms/CelebAMask-HQ.
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尽管最近在图像翻译方面进行了显着进展,但具有多种差异对象的复杂场景仍然是一个具有挑战性的问题。因为翻译的图像具有低保真度和微小对象,更少,并在对象识别中获得不满意的性能。如果图像的彻底对象感知(即,边界框,类别和掩码)作为先验知识,则在图像转换过程中将难以跟踪每个对象的样式转换。我们提出了基于Panoptic的对象样式对齐生成的对抗生成的对抗网络(POSA-GAN),用于图像到图像 - 图像到图像转换,以及一个紧凑的Panoptic semation数据集。 Panoptic分割模型用于提取Panoptic-Level感知(即,除去图像中的重叠的前景对象实例和背景语义区域)。这用于指导从目标域的样式空间采样的输入域图像和对象样式代码的对象内容代码之间的对齐。进一步转换样式对齐的对象表示以获得更高保真对象生成的精确边界布局。与不同的竞争方法系统的系统进行了系统地进行了系统地进行了系统地进行了系统地进行了比较,并对翻译图像的图像质量和物体识别性能进行了显着改善。
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